Valproate has been shown to be associated with a significant risk of birth defects and developmental disorders in children born to women who take valproate during pregnancy. ¹
- Other generic brands.
Valproate is a treatment for epilepsy and bipolar disorder and is prescribed to thousands of women. Since its introduction in 1974, the product information for doctors has included a warning about the possible risk of birth defects. As the risks to unborn children have been increasingly understood, the warnings have been strengthened. ¹