Sepsis is not easily definable in the first place. 2016 saw the Third International Consensus Definitions for Sepsis and Septic Shock. (1) This came from a process that involved two previous attempts to find consensus definitions, a recognition that none of the previous definitions were perfect, and a third brave attempt to find a definition for something that is somewhat amorphous.
The resulting definition: “life-threatening organ dysfunction caused by a dysregulated host response to infection” is a good one and I would agree with it.
However, it does little to help us diagnose sepsis in children. Recognising severe sepsis is not a great challenge. Recognising early sepsis in children is very difficult because of the way that children respond to illness.